Pregnancy During Active Surveillance of Papillary Thyroid Microcarcinoma

Abstract Introduction: Most patients diagnosed with papillary thyroid microcarcinoma (microPTC) classified as low risk and therefore eligible for active surveillance (AS) are women. Although age is a predictor of tumor progression (more frequent among young people), adults “appropriate” candidates AS. Consequently, proportion low-risk microPTC AS women childbearing knowledge the effect pregnancy on important. In Japanese population, Ito et al. observed this in only 8% pregnancies. None series outcomes western populations has so far reported behavior who became pregnant during Methods: We have submitted to Our management been not interrupt AS, i.e., indicate surgery when patient wishes become pregnant. report here results five their follow-up up 6 months after delivery. Results: The were 26 36 years old (median 29 years) they them had history radiation exposure, one family PTC, associated Hashimoto’s thyroiditis, all focus considered (but “ideal”) fact, was diagnosed, continued exhibit criterion according our initial protocol (tumor ≤ 1.2 cm, no apparent lymph node metastases [LNM] or extrathyroidal extension [ETE] ultrasonography [US]). All monitored by monthly measurement TSH levothyroxine (L-T4) administered maintain between 0.1 1 mIU/L. US performed (between 9 weeks gestation), around 22 weeks, at end pregnancy, During evaluations, none LNM ETE US. exhibited growth, defined an increase diameter ≥ 3 mm. Tumor growth 50% patient, small reduction Conclusions: preliminary suggest that high desire get should be exclusion factor References: Effects Pregnancy Papillary Microcarcinomas Thyroid Re-Evaluated Entire Patient Series Kuma Hospital. Y, Miyauchi A, Kudo T 2016; 26:156-60 AND Active Surveillance Adults Low-Risk Microcarcinomas: A Prospective Study. Rosario PW, Mourão GF, Calsolari MR. Horm Metab Res. 2019; 51:703-8.